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Serum methionine depletion without side effects by methioninase in metastatic breast cancer patients

Dominant effector genetics in mammalian cells

In aged animal models, growth hormone secretion is typically reduced by 50-70% compared to young adult levels, contributing to many of the physiological changes associated with aging including alterations in muscle mass, increased adiposity, reduced bone density, modified immune parameters, and decreased tissue repair capacity

Instead, the tripeptide -glutamylcysteinyl glycine (glutathione, GSH) appears to maintain the cellular redox homeostasis in most eukaryotes, Gram-negative bacteria, as well as some Gram-positive bacteria [27]

Gessert D

Berger P